Systems and Engineering Medicine

科学与工程，及数学和技术
- STEM的发展模式
Science and Engineering, and Mathematics and Technology
- STEM development model

世界三大经济中心
从南宋航海到意大利美第奇金融业，从明末实学到英国蒸汽机时代，发展到了“纽伦港”金融中心与工业技术路径。
从达芬奇 - 工程到伽利略 - 科学的转换，第谷和开普勒在捷克开启天体定量观测，孟德尔在捷克开创遗传规律分析，却是在意大利形成世界科学中心，而后，英国物理学与卡文迪许实验室，法国化学与实验医学，德国哥廷根与量子力学，美国计算机科学与贝尔实验室。
The world's three major economic centers
From Southern Song maritime navigation to the Italian Medici financial industry, from the practical learning of the late Ming Dynasty to the British steam engine era, it developed into "New York-London-Hong Kong" financial centers and industrial technology path.
The transition from Da Vinci - engineering to Galileo - science, Tycho Brahe and Johannes Kepler conducted quantitative astronomical observations in the Czech lands, and Gregor Mendel pioneered the analysis of the laws of heredity in the Czech lands, yet it was in Italy that the world center of science was formed, afterwards, Physics and the Cavendish Laboratory in the UK, Chemistry and Experimental Medicine in France, Gottingen and Quantum Mechanics in Germany Computer Science and Bell Labs in the US.

从科学到工业发展
宇宙与生命，文化与机器的研究，在本世纪，形成核心领域 - 人工智能与神经生物学机制，合成生物技术与发生遗传学机制，包括，基因片段组装合成，耐药细胞系连续突变筛选，序列标志片段显示分析，等。
复杂系统的整合学科模式，及其生物制造与精准医疗，并带来物理硬件-数字软件-生物湿件架构的机器设计。
From Science to Industrial Development-
The research of universe and life, culture and machines, in this century, core fields have been formed - artificial intelligence and neurobiological mechanisms, synthetic biotechnology and developmental genetic mechanisms, includes gene fragment assembly and synthesis, Continuous mutation screening of drug-resistant cell Lines, Sequence tagged fragment display analysis etc..
The integrative discipline model of complex systems, and its biomanufacturing and precision medicine, bringing about machine design based on the physical hardware-digital software-biological wetware architecture.

科学共同体
工程模型与受控实验的定量分析，实证科学带来实用工业的发展，高端技术的开拓一般是创新中心，前沿科学的开创一般是科学中心，并形成朝阳与夕阳领域的更新换代，新兴产业与传统行业的转型升级，从理论和概念与方法到技术 - 形成学科发展的群体效应。
国际大奖，比如，诺奖和拉斯克奖，挖掘历史，乃至开创与师从的接力棒谱系，颁发给在学术和技术源头层次的成就。
Scientific community
Quantitative analysis of engineering models and controlled experiments, empirical science brings about the development of practical industry, the development of high-end technologies generally serves as an innovation center, and the pioneering of frontier sciences serves as a science center, forming the renewal and replacement of sunrise and sunset sectors, as well as the transformation and upgrading of emerging industries and traditional sectors, formed group effects of disciplinary development from theory, concepts, and methods to technology.
International awards, such as the Nobel Prize and the Lasker Award, trace the lineage of discovery and mentorship, and awarded for achievements at the academic and technological frontier.

系统医学 - 系统与合成生物学
生物系统科学与工程 - Bj.Zeng的40年探索，1983年结构论纲领－2023年合成神经遗传学。
1-4轴心时代与4世界理论 - 城市群与地缘文化学，人文与科学 - 儒-释家与道-墨家，社会-心理学与生物-物理学，第3次机器革命与人机协同进化。
2-泛进化论 - 范畴论与组装理论，系统医学与图论-网络拓扑学，系统遗传学与细胞发生动力学，系统生物工程与纳米-生物电子学，生物系统理论与人工生物系统设计 - 生物信息学与化学生物学，细胞仿生学与转基因技术，等。
Systems Medicine - Systems and Synthetic Biology
Bio-systems Science and Engineering - 40 Years of exploration by Bj.Zeng, 1983 Outline of structure theory - 2023 Synthetic neurogenetics.
1-4 Axis Era and 4-World Theory - Cities groups and geoculturology, humanities and sciences - Rujiasm-Zenist and Daoism-Mohist, Social-Psychology and Bio-Physics, the 3rd machine revolution and human-machine co-evolution.
2-Pan-evolution theory - Category theory and assembly theory, systems medicine and graph theory-network topology, systems genetics and dynamics of cytogenesis, systems bioengineering and nano-bioelectronics, bio-systems theory and artificial bio-system design - Bioinformatics and chemical biology, cell biomimetics and transgenic technology, etc.